Director, Global Value and Access Strategy

Boston, MA, US.

The Director, GVAS role will serve as Market Access Lead for the chronic indications of our Pain portfolio, a series of novel non-opioid analgesics that have the potential to reshape the pain market. The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead the Global Commercial Team for chronic indications across the Vertex Pain portfolio.  The role reports to Sr Director, Pain Portfolio lead.  

Key Responsibilities:

  • Responsible for Global payer strategic planning to support value and access optimization for chronic indications for our Pain portfolio
    • Lead development of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process
      • Responsible for Global payer strategic planning to support value and access optimization; lead development of Global Payer Plan which integrates value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing
    • Accountable for ensuring the market access and payer perspective is reflected in cross-functional strategies (e.g. commercial, product development, regulatory affairs)
    • Ensure evidence prioritization required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access
    • Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs
    • Inform financial forecasts
    • Partner with Health Economics & Outcomes Research (HEOR), Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement
  • Co-lead Global Commercial Teams, and work cross-functionally and cross-regionally to develop optimal commercial strategies
    • The Global Commercial Team facilitates development of a commercial strategy in order to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy Team
    • This role should ensure collaboration and drive alignment across Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial success
  • Support P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment
  • Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly
  • Collaborate closely with HEOR, International P&R, Corporate Affairs, US Market Access, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization


  • 8+ years of direct biotechnology / pharmaceutical industry experience and/or payer experience
  • Deep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plus
  • Experience in leading cross-functional teams required
  • Experience in specialty and/or rare disease access models preferred
  • Demonstrated ability to think strategically and make sound pricing and market access recommendations
  • Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to “make things happen”
  • Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex
  • General experience in commercialization and drug development
  • Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex
  • Demonstrated relationship building at all levels of the organization and across geographies
  • Recognized as a team player with excellent interpersonal skills who is flexible and reliable
  • Displays sound ethics and a fit for Vertex’s core values


  • BA/BS in field of study requiring quantitative analysis; advanced degree preferred

Company Information

Vertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) as well as Casgevy, a new gene therapy for sickle cell disease and beta-thalassemia.  Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, APOL-1 mediated kidney disease (AMKD), and cell therapies for Type 1 diabetes, among others.   

In consideration of our expanding pipeline and an increasingly complex and challenging Global market access environment, Vertex is expanding its Global Value and Access Strategy (GVAS) team. Market Access is a key commercial function that ensures transformative Vertex therapies are appropriately funded and ultimately make it into the hands of the patients around the world.  The GVAS team works cross-functionally and across regions to ensure the payer view is represented in commercial and development plans across the lifecycle.  We are driven by a desire to deliver groundbreaking pricing & reimbursement solutions to allow our medicines to reach patients faster than ever before.  

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition.

This job is posted by Vertex.


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