Global Project Manager – RWE

Jobs at Novo Nordisk for Health Economists

Bangalore, India. Novo Nordisk, a global healthcare leader, is seeking a Senior Global Project Manager to join our Real-World Evidence Operations team in the Regions & Operations Department of Global Medical Affairs, Global Business Services (GBS), based in Bangalore. Job Description: As as Global Project Manager, Real-World Evidence, you will lead complex, global real-world evidence studies and non-interventional studies. You … Read more

RWE Associate Director

Vertex Health Economics jobs

Boston, MA, US. The Real World Evidence (RWE) Associate Director is an integral member of the RWE team, who leverages expertise in epidemiology and real world data to develop fit-for-purpose observational research, and to inform internal and external stakeholders on natural history (NH) of disease and real world outcomes within their assigned therapeutic area. The RWE Associate Director works cross-functionally … Read more

Director Global HEOR

Ipsen Jobs for Health Economists

London, UK / Boulogne, France. The Director Global HEOR will be part of the Global Value & Access Team collaborating closely with colleagues in Market Access & Pricing, Marketing, Clinical Development, Research and Development, Market Research, Regulatory Affairs, Medical Affairs and Strategic Planning, to deliver critical strategic value evidence generation in support of access to Ipsen’s products spanning early development, … Read more

Summer Internship: HEOR Intern

Jobs for health economist at BeiGene

Home-based, US. Note: To be considered for our 2025 Summer Internship program you must be enrolled in a university degree program and cannot be graduating sooner than December 2025.  Education Required: Currently pursuing PhD in Health Economics, Outcomes Research, Pharmacoeconomics, Epidemiology, Health services Research or related discipline. General Description: The HEOR summer intern will actively contribute to various oncology HEOR … Read more

(Senior) Manager Market Access

Jobs at Daiichi Sankyo for Health Economists

Zurich, Switzerland. We are seeking highly qualified candidates to fill the position: (Senior) Manager Market Access Switzerland (m/f/x). The Position: The (Senior) Manager Market Access is a key role within our Market Access Department and will be responsible to devise the overall local market access strategy and ensure timely execution of the market access deliverables for the assigned products/indications. The … Read more

National Value and Access Specialist

Jobs at Daiichi Sankyo for Health Economists

Madrid, Spain. Reporting to the National Value and Access Manager at Daiichi Sankyo Spain for Specialties division, this role will engage decision makers/payers to gain & maintain access of our medicines at national/regional/local levels, at the right time and in the best pricing & reimbursement conditions possible. Additionally, the role includes monitoring and analyzing the impacts of regulatory and pharmaceutical … Read more

Director HEOR

Jobs at Bayer for Health Economists

Home-based, US. Lead the development and implementation of U.S. Data Generation and Observational Studies (DG&OS) research in the field for the Bayer. product portfolio; Be responsible for DG&OS research plans with customers to meet their informational needs; Design and conduct studies including outcomes, economics and epidemiology studies; Interact with Managed Care Organization (MCOs), Center for Medicare and Medicaid Services (CMS), Key Opinion … Read more

Manager HEOR

Jobs at Philips Healthcare for Health Economists

MA / CA / IL, US. You will generate HEOR real-world evidence to drive patient access to diverse innovations from Philips businesses being part of the global Health Economics team within the Health Economics, Market Access, and Reimbursement Department. Your role: You’re the right fit if:  How we work together We believe that we are better together than apart. For … Read more

Director, HEOR

Jobs at Philips Healthcare for Health Economists

Plymouth, MN / Cambridge, MA, US. This role is responsible for leading the creation of real-world evidence to support Philips’ global business units. This role encompasses disease and market landscaping, observational and database studies. Partnering with Clinical Affairs and Market Access, the Director ensures compliance and engages with healthcare experts to stay current on trends. They also manage talent, advancing … Read more

Associate Principal, RWE

Jobs for health economists at Avalere Health

Home-based, US. Avalere Health is seeking an Associate Principal to join our Evidence & Strategy practice who has extensive expertise in health economics & outcomes research, evidence strategy, and value assessment. The candidate should have extensive experience conducting quantitative and qualitative research using a variety of methodologies, providing strategic and tactical HEOR/Value & Evidence advisory services to a variety of … Read more

Associate Director, Global RWE & Health Outcomes Research

Health economics jobs GSK

UK / Belgium / US. The role of Associate Director, Global Real-World Evidence & Health Outcomes Research, Evidence Synthesis is critical to achieving this ambition by ensuring that each medicine GSK brings to market is supported by scientifically credible, high-quality evidence that drives competitiveness and strong evidence-based product positioning, value propositions and value-based pricing.  Associate Director, Evidence Synthesis works in … Read more

HEOR Specialist or Manager

Jobs at Novo Nordisk for Health Economists

Tokyo, Japan. As a HEOR Specialist, you will have the opportunity to implement Health Economic Outcomes Research (HEOR) projects in line with value proposition, market access, and scientific exchange strategies for assigned products and therapeutic areas. You will also support the HEOR manager in securing timely Health Technology Assessment (HTA) submissions and optimal market access and pricing through preparing and … Read more

Director, US HEOR & RWE

Ipsen Jobs for Health Economists

Home-based, Berkeley Heights, NJ, US. The Director of US Health Economics and Outcomes Research & Real-World Evidence (HEOR & RWE) is responsible for identifying real-world and economic evidence needs and developing the real-world and economic evidence generation plans in collaboration with internal business partners to support the value of our products for US healthcare providers, population-health decision makers, and other … Read more

Associate Director – HEOR

Vertex Health Economics jobs

Paris, France. Vertex is seeking a talented individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. As a member of the International Health Economics and Outcomes Research team, your primary responsibility will be to support launch execution, local real world evidence generation and … Read more

Head, Global RWE & Health Outcomes Research

Health economics jobs GSK

Tokyo, Japan. The Japan Head, Real-World Evidence & Health Outcomes Research will be the overall leader of the non-interventional data generation team for the Japan business.  Accountabilities include management and development of a team of leaders and scientists with expertise in real-world evidence and other non-interventional study methods. This role will ensure that team members engage closely with Japan and global … Read more

Real-World Evidence in Health Economics

RWE jobs in Health Economics
Real-World Evidence in Health Economics

Real-world evidence (RWE) has become an increasingly important aspect of health economics research in recent years. It provides a comprehensive and in-depth understanding of how different health interventions work in real-world settings.

What is Real-World Evidence?

Real-world evidence (RWE) is defined as data collected from sources other than traditional randomized controlled trials (RCTs). These data come from a variety of sources, including electronic health records (EHRs), claims databases, registries, patient-reported outcomes (PROs), and surveys.

RWE allows researchers to evaluate the effectiveness, safety, and cost-effectiveness of health interventions in real-world settings. This is important because RCTs often have strict inclusion and exclusion criteria, which means that the results may not be generalizable to real-world populations.

Importance of Real-World Evidence in Health Economics

RWE is becoming increasingly important in health economics because it provides a more complete picture of the effectiveness and safety of health interventions. By using RWE, researchers can evaluate how interventions work in a variety of settings and patient populations, which can help inform clinical practice and policy decisions.

RWE can also be used to conduct cost-effectiveness analyses, which help policymakers determine the value of health interventions. Cost-effectiveness analyses compare the costs and benefits of different health interventions, taking into account the costs of the intervention as well as the costs of any adverse events or complications that may occur.

Differences between RWE and Randomized Controlled Trials (RCTs)

RCTs are considered the gold standard for evaluating the effectiveness and safety of health interventions. However, there are several key differences between RWE and RCTs.

RCTs are conducted under controlled conditions and have strict inclusion and exclusion criteria, which means that the results may not be generalizable to real-world populations. RWE, on the other hand, is collected from a variety of sources and reflects the real-world experiences of patients.

RCTs also tend to be shorter in duration than RWE studies, which means that they may not capture the long-term effects of health interventions. RWE studies, on the other hand, can provide information on the long-term effectiveness and safety of interventions.

Methods of Collecting RWE

There are several methods of collecting RWE, including:

Electronic Health Records (EHRs)
EHRs are digital records of patient health information that are maintained by healthcare providers. EHRs can provide a wealth of information on patient demographics, diagnoses, treatments, and outcomes.

Claims Databases
Claims databases contain information on healthcare services and medications that are billed to insurance providers. Claims data can provide information on healthcare utilization, costs, and outcomes.

Registries
Registries are databases that collect information on specific diseases or health conditions. They can provide valuable information on disease prevalence, treatment patterns, and outcomes.

Patient-Reported Outcomes (PROs)
PROs are questionnaires or surveys completed by patients that assess their health status, symptoms, and quality of life. PROs can provide information on patient preferences and experiences with different interventions.

Surveys
Surveys can be used to collect information on patient demographics, health behaviors, and healthcare utilization. They can also be used to assess patient preferences and satisfaction with different interventions.

Advantages of Real-World Evidence

There are several advantages of using RWE in health economics research, including:

  • RWE reflects real-world experiences and can provide a more comprehensive understanding of the effectiveness and safety of interventions.
  • RWE can be used to evaluate interventions in a variety of settings and patient populations.
  • RWE can provide information on the long-term effectiveness and safety of interventions.
  • RWE can be used to conduct cost-effectiveness analyses, which can inform clinical practice and policy decisions.

Challenges and Limitations of Real-World Evidence

There are several challenges and limitations to using RWE in health economics research, including:

  • RWE can be subject to bias and confounding, which can affect the validity of the results.
  • RWE can be difficult to collect and analyze, particularly when using multiple data sources.
  • RWE may not be as well-suited for evaluating rare diseases or interventions.

Applications of Real-World Evidence

RWE has several applications in health economics research, including:

Health Technology Assessment
Health technology assessment (HTA) is a process that evaluates the clinical effectiveness, safety, and cost-effectiveness of new health technologies. RWE can be used in HTA to provide information on the real-world effectiveness and safety of interventions.

Comparative Effectiveness Research
Comparative effectiveness research (CER) compares the effectiveness of different interventions for the same health condition. RWE can be used in CER to compare the effectiveness of interventions in different patient populations and settings.

Post-Marketing Surveillance
Post-marketing surveillance is the process of monitoring the safety and effectiveness of new drugs and medical devices after they have been approved for use. RWE can be used in post-marketing surveillance to monitor the long-term safety and effectiveness of interventions.

Future of Real-World Evidence in Health Economics

RWE is likely to become increasingly important in health economics research in the future. Advances in technology and data analytics are making it easier to collect and analyze RWE, and policymakers are recognizing the importance of using RWE to inform clinical practice and policy decisions.