United States » HEOR Director

HEOR Director

Boston, MA, US.

Vertex is seeking a talented individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society.

As a member of our Global HEOR team based in the Boston Seaport District, your primary responsibility will be to envision, create and communicate compelling evidence supporting the value of the Cystic Fibrosis portfolio. Using your deep research expertise, you will lead evidence generation supporting the value proposition of Vertex’s assets in Cystic Fibrosis with a focus on prospective and site-based studies.  This is a hybrid role, reporting to the Sr. Director HEOR/CF Lead with the possibility of one or more direct reports. 

Key Responsibilities:

  • Collaborate to ensure global evidence generation plans are tailored to address global evidence needs across the cystic fibrosis portfolio.
  • Represent the Global HEOR team in internal cross-functional evidence generation activities and work closely with other evidence generating functions in the global organization (Medical, Biostatistics, Safety, Clinical development).
  • Ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; be accountable for study design, data analysis and the quality of the evidence produced.
  • Identify and vet third party vendors, oversee the RFP process including defining scope, budgets and timelines, act as a key point of contact throughout project execution to ensure quality and timely execution.
  • Ensure compliance with all internal governance processes including those related to protocol review, interactions with KOLs, reporting of safety data and publication
  • Clearly communicate study findings to internal and external stakeholders, lead conference submissions and peer-reviewed publications and ensure evidence is communicated appropriately to key stakeholders
  • Act as subject matter expert in real world evidence generation across the Global organization.

 Key Requirements:

  • Advanced degree (PhD, MD, MPH, MS or PharmD) in a scientific discipline; clinical background should be supplemented with advanced quantitative training demonstrated by an MPH or MS in a relevant field
  • Minimum of 10 years of relevant experience, with substantial background in conducting both prospective (e.g., survey, site-based) and retrospective (e.g., chart review, registry) studies; experience with PROs is preferred
  • Excellent written and verbal communication skills; track record of publication in peer-reviewed journals
  • Subject-matter expert in methods for real-world evidence generation with extensive experience shaping and generating scientific analysis to support value propositions in a consulting and/or pharmaceutical environment; experience within a pharmaceutical company preferred.
  • Excellent project management and people management skills to oversee vendors and internal team and ensure successful project execution
  • Culturally sensitive collaborator able to effectively lead cross-functional teams to drive alignment with business and stakeholder needs while managing to timelines and budgets
  • Strong verbal communications skills, including presentation skills; comfortable communicating complex concepts and adapting presentation style to a variety of audiences including senior executives
  • Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Please note that Vertex requires COVID-19 vaccination for all employees working in the U.S. as a condition of employment at Vertex, subject to medical, religious or other accommodations or exemptions required by law. We believe this requirement is vital to keeping everyone at Vertex and in our communities safe. This requirement applies to both existing and new employees who may at any time work on-site at a Vertex facility or visit another location on behalf of Vertex (e.g., conferences, customer visits, etc.), including all remote employees. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition.

This job is posted by Vertex.


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