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Evidence Generation Manager

London, UK.

Are you looking for a patient-focused, innovation-driven company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as our Market Access Evidence Generation Manager in our UK Head Offices in Central London Paddington.

The Market Access Evidence Generation Manager, HTA Centre of Excellence brings together technical knowledge of cost-effectiveness methods used in HTA and a broader awareness of market access and commercial strategy to help shape the development of Takeda’s innovative pipeline.

This is a highly collaborative role interacting with multiple internal functions at the Global, Regional (EUCAN) and Local Operating Country (LOC) level as well as externally with health care professionals (HCPs) and Patient Organisations to deliver prioritised, strategic recommendations for pipeline programs.

This role requires proactivity, strong interpersonal skills, and the ability to work on a broad range of projects as you work autonomously and as part of larger teams across a wide range of therapeutic areas.

Key Accountabilities:

  • Deliver prioritised, strategic recommendations on the evidence requirements for pipeline assets (Phase 1 onwards) to Global Program Teams, based on patient, payer, prescriber and LOC needs.
  • Support in the shaping of clinical development programmes and Global evidence generation plans to ensure the evidence required for patient access in cost-effectiveness-driven markets is incorporated and consistent with the overarching commercial strategy and product value proposition.
  • Validate, stress test, and advise on Global access strategy, pricing, and launch scenarios.
  • Collaborate with cost-effectiveness LOCs to understand, collect, and consolidate their key evidence needs for HTA across the Takeda pipeline.
  • Provide strategic guidance and support in the planning and execution of evidence generation activities in the UK LOC, EUCAN, Global, and other cost-effectiveness markets where appropriate.
  • Support in the identification and early engagement of HCPs, Patient Organisations, health economists and HTA experts to inform Global and local strategy and build long term relationships with Takeda.
  • Collaborate across functions within the UK LOC to ensure that local insights are embedded in Global pipeline asset strategy.
  • Collaborate across functions to drive early understanding of new disease backgrounds, therapeutic landscape, competitive intelligence, stakeholders, data sources and HTA landscape in the UK.
  • Collaborate with Global and UK Health Economics Teams to develop early economic models and support health economics-related activities.
  • Critique and/or run analyses and publish key scientific findings in high-impact journals, on topics including: meta-analysis/extensive statistical analysis, outcome research, indirect comparisons, health economic modelling.
  • Deputise as appropriate for the Head of Appraisals and Centre of Excellence at both external and internal meetings.
  • Ensure continuous knowledge transfer of early pipeline development and strategy initiatives through to teams responsible for HTA submissions.

Key Skills, Knowledge and Experience:


  • MSc or PhD in a scientific area (human biology, medicine, statistics, health economics, health policy). Pharmacist or other Health Care Professional. Postgraduate qualification in health economics or related field.


  • Several years of experience in the pharmaceutical industry/CRO in evidence generation (health economic modelling/ outcome research/ data analysis). Experience leading a diverse set of evidence generation activities (e.g. health economic modelling, real world evidence [RWE], indirect treatment comparisons, patient reported outcome [PRO] development).
  • Demonstrated experience collaborating with senior internal and external stakeholders and working across matrix teams.
  • Experience leading development of multiple HTAs from planning through to successful decision.
  • Strong understanding of the pharmaceutical industry and lifecycle of pharmaceutical products. Understanding of medical terminology and clinical development. Understanding of the National Health Service (NHS) and decision processes involved in bringing drugs to market, prescribers and patients.
  • Knowledge of horizon scanning and HTA organisations and other key external stakeholder bodies.
  • Highly proactive, well organised and goal orientated with an excellent track record of meeting deadlines.
  • Ability to make decisions and communicate rationale in high pressure environments.
  • Positive work ethic with the ability to pivot and be flexible in a fast-moving environment.
  • Excellent networking skills and ability to influence upwards and laterally


  • Experience of working within the NHS.
  • Experience of commercial strategy development.
  • Sound knowledge of regulatory procedures and clinical trial design.
  • Strong track record of publications in renowned scientific journals.
  • Knowledge of healthcare systems outside of UK.
  • Knowledge of international reference pricing.
  • Significant customer facing experience
  • Forward thinker with the ability to spot and prioritise organisational needs.
  • Ability to coach/mentor others.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realise their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

What Takeda Can Offer You

To further support and inspire our employees, our benefits include: Competitive basic salary, Annual Bonus, Company Car Benefit (dependent on role) Contributory Pension Scheme, Private Health Cover and Life Assurance.

Empowering Our People to Shine


GBR – Paddington

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Time Type

Full time

This job is posted by Takeda.


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