Global HEOR Business Partner

Sanofi Health Economists jobs

Cambridge, MA / Bridgewater, NJ, US. To support Oncology portfolio to plan and generate robust health economics and value-based evidence to maximize the value propositions from both a global and US perspective working within the Market Access tripod. Major Activities / Key Responsibilities Health Economics strategy, evidence generation and reimbursement support Deliver quality research projects, economic models, trial design recommendations … Read more

Health Economics Associate (Advanced Analytics)

Parexel Health Economics jobs

Home-based, Sweden. Advanced Analytics Associate will support in ensuring that all assigned projects are being conducted in an efficient manner and that quality and client satisfaction is maximized at all times — ensuring the direction of the project and the quality of the deliverables meet the project objectives and the client needs. The Associate will support in maintaining client relationships … Read more

Director, HEOR Product Lead

Novartis Health Economics jobs

Home-based, US. This role is to enable the HEOR Immunology function to achieve excellence in value-based evidence strategy to support access, differentiation, and patient outcomes. The Director is directly responsible for managing relationships with the appropriate Medical Directors and commercial leads (e.g. Value and Access) to ensure alignment on strategic priorities for efficient and impactful tactical execution. The Director along … Read more

Associate Director, HEOR Product Lead

Novartis Health Economics jobs

Home-based, US. This role is to enable the HEOR Neuroscience/ Gene Therapeutics (GTx) function to achieve excellence in value-based evidence strategy to support access, differentiation, and patient outcomes. The Associate Director is directly responsible for managing relationships with the appropriate Medical Directors and commercial leads (e.g. Value and Access) to ensure alignment on strategic priorities for efficient and impactful tactical … Read more

Research Scientist – RWE

Precision Medicine Group Health Economics Jobs

Home-based, US. Are you looking to work with a dynamic team of industry leading professionals in the HEOR space? Is your passion leading Real World Evidence studies that improve healthcare outcomes worldwide? Our Real World Evidence team is hiring a Research Scientist to join our team of research professionals conducting real-world studies in the pharmacy and biotech space; operating as a … Read more

Manager, HEOR

Bristol Myers Squibb Jobs for Health economists

Otemachi, Japan. Are you a HEOR professional looking to further your career? We are seeking a dedicated individual with a strong foundation in epidemiology, health-related research, economics, or statistics. Ideal candidates will have hands-on experience in the following types of studies: Systematic/targeted literature review. Database studies. Patient-reported outcomes (PRO). Meta-analyses. Mathematical modeling/simulations. This role involves working closely with a senior … Read more

Director – US, RWE and Health Outcomes

Health economics jobs GSK

Durham, NC / Philadelphia, PA, US. The Director – US, Real World Evidence and Health Outcomes, Hepatology, linerixibat reportsto the Therapeutic Area Head, Specialty Medicines. The incumbent will provide leadership in developing and executing a quality, strategically aligned research agenda, focused on relevant, high impact evidence package to demonstrate the value of late stage development and US marketed assets in the … Read more

Global HEOR Director

Jobs at G&J Lee Recruitment for Health Economists

London, UK / Paris, France. Exclusive To Gareth Lee – This Position Is Not Available Via Another Recruiter. Global Pharmaceutical company, Rare Disease portfolio. Location: London, UK or Paris, France (Hybrid with 2-3 days per week required in the office). Salary: Up to €150k plus package. This is a new, rare disease focused Global position within the HEOR & Market … Read more

Senior Manager, HEOR RWE Analytics

Jobs at Abbvie for Health Economists

Mettawa, IL, US. Role is responsible for designing and executing analytical components of plans for research studies that examine the real-world value of pharmaceutical assets or address strategic questions in the disease areas of interest to AbbVie. Position applies methodological and analytical expertise to conduct the analysis of V&E research studies. This involves the application of real-world evidence study design, … Read more

Associate Director RWE Manager

Novartis Health Economics jobs

Ireland / UK /  India. The Associate Director will support RWE Executive Directors in developing and executing RWE strategies for molecules within a disease area as well as the execution of Real World Evidence activities, in particular, non-interventional studies (NIS). This position can be located in Ireland, UK or Hyderabad. About the Role Major accountabilities: Support the development and implementation … Read more

Real-World Evidence in Health Economics

RWE jobs in Health Economics
Real-World Evidence in Health Economics

Real-world evidence (RWE) has become an increasingly important aspect of health economics research in recent years. It provides a comprehensive and in-depth understanding of how different health interventions work in real-world settings.

What is Real-World Evidence?

Real-world evidence (RWE) is defined as data collected from sources other than traditional randomized controlled trials (RCTs). These data come from a variety of sources, including electronic health records (EHRs), claims databases, registries, patient-reported outcomes (PROs), and surveys.

RWE allows researchers to evaluate the effectiveness, safety, and cost-effectiveness of health interventions in real-world settings. This is important because RCTs often have strict inclusion and exclusion criteria, which means that the results may not be generalizable to real-world populations.

Importance of Real-World Evidence in Health Economics

RWE is becoming increasingly important in health economics because it provides a more complete picture of the effectiveness and safety of health interventions. By using RWE, researchers can evaluate how interventions work in a variety of settings and patient populations, which can help inform clinical practice and policy decisions.

RWE can also be used to conduct cost-effectiveness analyses, which help policymakers determine the value of health interventions. Cost-effectiveness analyses compare the costs and benefits of different health interventions, taking into account the costs of the intervention as well as the costs of any adverse events or complications that may occur.

Differences between RWE and Randomized Controlled Trials (RCTs)

RCTs are considered the gold standard for evaluating the effectiveness and safety of health interventions. However, there are several key differences between RWE and RCTs.

RCTs are conducted under controlled conditions and have strict inclusion and exclusion criteria, which means that the results may not be generalizable to real-world populations. RWE, on the other hand, is collected from a variety of sources and reflects the real-world experiences of patients.

RCTs also tend to be shorter in duration than RWE studies, which means that they may not capture the long-term effects of health interventions. RWE studies, on the other hand, can provide information on the long-term effectiveness and safety of interventions.

Methods of Collecting RWE

There are several methods of collecting RWE, including:

Electronic Health Records (EHRs)
EHRs are digital records of patient health information that are maintained by healthcare providers. EHRs can provide a wealth of information on patient demographics, diagnoses, treatments, and outcomes.

Claims Databases
Claims databases contain information on healthcare services and medications that are billed to insurance providers. Claims data can provide information on healthcare utilization, costs, and outcomes.

Registries
Registries are databases that collect information on specific diseases or health conditions. They can provide valuable information on disease prevalence, treatment patterns, and outcomes.

Patient-Reported Outcomes (PROs)
PROs are questionnaires or surveys completed by patients that assess their health status, symptoms, and quality of life. PROs can provide information on patient preferences and experiences with different interventions.

Surveys
Surveys can be used to collect information on patient demographics, health behaviors, and healthcare utilization. They can also be used to assess patient preferences and satisfaction with different interventions.

Advantages of Real-World Evidence

There are several advantages of using RWE in health economics research, including:

  • RWE reflects real-world experiences and can provide a more comprehensive understanding of the effectiveness and safety of interventions.
  • RWE can be used to evaluate interventions in a variety of settings and patient populations.
  • RWE can provide information on the long-term effectiveness and safety of interventions.
  • RWE can be used to conduct cost-effectiveness analyses, which can inform clinical practice and policy decisions.

Challenges and Limitations of Real-World Evidence

There are several challenges and limitations to using RWE in health economics research, including:

  • RWE can be subject to bias and confounding, which can affect the validity of the results.
  • RWE can be difficult to collect and analyze, particularly when using multiple data sources.
  • RWE may not be as well-suited for evaluating rare diseases or interventions.

Applications of Real-World Evidence

RWE has several applications in health economics research, including:

Health Technology Assessment
Health technology assessment (HTA) is a process that evaluates the clinical effectiveness, safety, and cost-effectiveness of new health technologies. RWE can be used in HTA to provide information on the real-world effectiveness and safety of interventions.

Comparative Effectiveness Research
Comparative effectiveness research (CER) compares the effectiveness of different interventions for the same health condition. RWE can be used in CER to compare the effectiveness of interventions in different patient populations and settings.

Post-Marketing Surveillance
Post-marketing surveillance is the process of monitoring the safety and effectiveness of new drugs and medical devices after they have been approved for use. RWE can be used in post-marketing surveillance to monitor the long-term safety and effectiveness of interventions.

Future of Real-World Evidence in Health Economics

RWE is likely to become increasingly important in health economics research in the future. Advances in technology and data analytics are making it easier to collect and analyze RWE, and policymakers are recognizing the importance of using RWE to inform clinical practice and policy decisions.